The following products have shown to have excellent binding and stability
characteristics in protein chemistry J.Amer.oil Chem. Soc., Apr., 1962, Vol.XXXIX,
No.4, Methods of Analyzing Industrial Aliphatic Liquids, Mangolds, H.K. and
Kammereck, R., U. of Minn., The Hormel Institute, Austin, Minn.
An example of their use is where native BSA has a total of ten binding sites to C8-C14
sulfates and C8-C12 sulfonates. The number os sites increases with hydrocarbon tail
length, and while the interaction energy is not a function of chain length in the case of
sulfates, it becomes chain length dependent in the case of sulfonates. Binding
affinities are also strongly dependent on the character of the polar portionof the
ligand:sulfate and sulfonate groups participate with different energy contributions.
Also, for the measurement of the binding isotherms and the corresponding interaction
energies for alkyl sulfates and sulfonates on proteins, as well as ORD and viscosity
data, furnishing important knowledge on the short-range forces and the molecular
shape of proteins.
Additional elaboration of this area can be found in "Multiple Equilibria In Proteins",
Acac. Press, N.Y. (1969) by J.Steinhart and J.Reynolds. All products are analyzed by
elemental analysis and occasionally by GC, reflecting purities of 98-99+%.
Aklyl Sulphate and Sulfonate Kits are available to those desiring a small amount of
each product for initial investigations. Larger amounts including kilo amounts can be
prepared upon request.
We have recently added Heptyl and Octyl sulfonate as the ammonium salt.
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